Zhang W, Nuki G, Moskowitz RW, Abramson S, Altman RD, Arden NK, Bierma-Zeinstra S, Brandt KD, Croft P, Doherty M, Dougados M, Hochberg M, Hunter DJ, Kwoh K, Lohmander LS, Tugwell P (2010) OARSI recommendations for the management of hip and knee osteoarthritis: part III: changes in evidence following systematic cumulative update of research published through January 2009
Successful long-term weight management often includes: Consistent eating patterns Balanced nutrition Physical activity Ongoing metabolic monitoring Some patients continue medication long term to maintain results, while others transition to lower maintenance doses or lifestyle-based strategies
It should be used alongside a reduced-calorie diet and increased physical activity
This is not a contraindication in the UK SmPC, but clinicians should remain vigilant for thyroid-related symptoms in all patients, including those with autoimmune thyroid disease